STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1922DUF354 multi-domain protein. (365 aa)    
Predicted Functional Partners:
TSIB_1920
UDP-N-acetylglucosamine 2-epimerase.
 
    0.663
TSIB_1921
UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.629
TSIB_1047
Predicted protein kinase, putative.
  
     0.593
TSIB_1154
RNA-binding protein, containing THUMP domain.
  
     0.562
TSIB_0860
Predicted transcription regulator, containing cell wall binding repeat 2 and DNA-binding HTH domains.
  
    0.547
TSIB_1343
Probable brix domain-containing ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
     0.519
priS
Probable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...]
  
     0.487
TSIB_0418
Oligosaccharyl transferase STT3 subunit superfamily.
  
     0.476
TSIB_1841
Integral membrane protein, putativ.
  
     0.476
rnp3
Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.465
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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