STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1982Daunorubicin resistance ABC transporter membrane protein. (249 aa)    
Predicted Functional Partners:
TSIB_1983
Daunorubicin resistance ATP-binding protein DrrA.
 
  
 0.896
TSIB_1984
Hypothetical protein.
       0.774
TSIB_0213
ABC-type multidrug transport system, ATPase component.
 
  
 0.765
TSIB_1985
Hypothetical protein.
       0.714
TSIB_1371
ABC-type multidrug transport system, ATPase component.
 
  
 0.654
TSIB_0142
Daunorubicin resistance ATP-binding protein.
 
  
 0.595
TSIB_0172
Membrane-associated metalloprotease, CaaX family.
  
  
 0.549
mtnP
Purine-nucleoside phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
  
    0.533
TSIB_0350
NAD(P)H-flavin oxidoreductase.
 
  
 0.522
TSIB_0590
ABC-type multidrug transport system.
 
  
 0.511
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.