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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1998Short-chain alcohol dehydrogenase. (242 aa)    
Predicted Functional Partners:
TSIB_0703
Short-chain alcohol dehydrogenase.
  
  
 
0.919
TSIB_1997
Hypothetical protein.
       0.710
TSIB_1995
Hypothetical protein.
       0.705
TSIB_1996
Hypothetical protein.
       0.703
TSIB_1999
Phospholipid-binding protein, PBP family.
  
 
 0.681
mre11
DNA double-strand break repair protein mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
 
 
 0.613
mre11-2
DNA double-strand break repair Mre11 nuclease; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
 
 
 0.611
TSIB_1906
Membrane-bound NADP+-reducing complex MBX, subunit MbxL (dehydrogenase subunit); Belongs to the complex I 49 kDa subunit family.
  
 
 0.558
TSIB_1907
Membrane-bound NADP+-reducing complex MBX, subunit MbxK (dehydrogenase subunit).
   
 
 0.557
TSIB_1908
Membrane-bound NADP+-reducing complex MBX, subunit MbxJ (dehydrogenase subunit).
  
 
 0.551
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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