Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TSIB_2019Pyrophosphorylase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (472 aa)    
Predicted Functional Partners:
TSIB_2020
CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase.
 
  
 0.937
TSIB_0615
Probable L-threonine 3-dehydrogenase.
  
  
 0.860
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.854
TSIB_0800
Acetyl-CoA acetyltransferase.
  
 
 0.820
TSIB_0428
Bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase.
    
 0.817
TSIB_1274
Bifunctional phosphatase/dolichol-phosphate glucosyltransferase.
  
 
 0.817
TSIB_2021
Glycosyl transferase.
  
  
 0.812
TSIB_1233
Bifunctional short chain isoprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
  
 0.792
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 0.755
TSIB_0440
Orotidine 5'-phosphate decarboxylase.
   
 
 0.748
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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