Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TSIB_2030DNA polymerase, beta domain protein region. (133 aa)    
Predicted Functional Partners:
TSIB_2029
HEPN domain protein.
 
 
   0.961
TSIB_2028
Pleiotropic regulatory protein degT; Belongs to the DegT/DnrJ/EryC1 family.
       0.778
TSIB_2031
NADH dependent dehydrogenase like protein.
       0.777
TSIB_2032
NDP-sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
       0.773
TSIB_2027
CysE serine O-acetyltransferase.
       0.768
TSIB_0665
Predicted glutamine amidotransferase, class II.
  
     0.551
TSIB_2025
Glycosyltransferase.
       0.548
TSIB_2026
Glycosyl transferase family 2.
       0.548
TSIB_1752
ABC-type dipeptide/oligopeptide transport system, probable periplasmic component.
  
     0.473
TSIB_1334
Hypothetical protein.
  
     0.471
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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