Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_2041IS element ISTsi1 orfB, putative transposase. (393 aa)    
Predicted Functional Partners:
TSIB_2042
IS element ISTsi1 orfA, putative resolvase.
 
  
 0.918
TSIB_0261
IS element ISTsi3 orfB, probably transposase.
  
     0.667
TSIB_1735
IS element ISTsi1 orfA, putative resolvase.
 
  
 0.656
TSIB_2043
DUF1814 domain containing protein.
       0.567
TSIB_0260
IS element ISTsi3 orfA-like, probably transposase.
 
   
 0.564
TSIB_2044
Glucose-1-phosphate thymidylyltransferase.
 
     0.463
TSIB_1615
DUF55 domain containing protein; Belongs to the UPF0310 family.
  
     0.461
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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