BG61_18020 protein (Caballeronia glathei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

BG61_18020

Unannotated protein. (648 aa)

Predicted Functional Partners:

BG61_10785

0.857

BG61_10790

0.832

cpsB

0.731

cpsB-2

0.731

BG61_16170

0.731

BG61_02895

0.730

BG61_35915

0.717

BG61_32810

0.717

BG61_32760

0.717

BG61_18805

0.717

Your Current Organism:

Caballeronia glathei

NCBI taxonomy Id: 60547
Other names: ATCC 29195, Burkholderia glathei, C. glathei, CFBP 4791, CIP 105421, DSM 50014, JCM 10563, LMG 14190, LMG:14190, Paraburkholderia glathei, Pseudomonas glathei, strain N 15, strain N15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BG61_02895	BG61_16170	GCA_000751215_05400	GCA_000751215_02714	Unannotated protein; Belongs to the glycosyl hydrolase 26 family.	Unannotated protein; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.481
BG61_02895	BG61_18020	GCA_000751215_05400	GCA_000751215_05991	Unannotated protein; Belongs to the glycosyl hydrolase 26 family.	Unannotated protein.	0.730
BG61_02895	cpsB	GCA_000751215_05400	GCA_000751215_00695	Unannotated protein; Belongs to the glycosyl hydrolase 26 family.	Unannotated protein; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.481
BG61_02895	cpsB-2	GCA_000751215_05400	GCA_000751215_02687	Unannotated protein; Belongs to the glycosyl hydrolase 26 family.	Unannotated protein; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.481
BG61_10785	BG61_10790	GCA_000751215_06010	GCA_000751215_06009	Unannotated protein.	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	0.999
BG61_10785	BG61_18020	GCA_000751215_06010	GCA_000751215_05991	Unannotated protein.	Unannotated protein.	0.857
BG61_10785	BG61_18805	GCA_000751215_06010	GCA_000751215_04238	Unannotated protein.	Unannotated protein.	0.439
BG61_10785	BG61_32760	GCA_000751215_06010	GCA_000751215_02540	Unannotated protein.	Unannotated protein.	0.439
BG61_10785	BG61_32810	GCA_000751215_06010	GCA_000751215_02530	Unannotated protein.	Unannotated protein.	0.439
BG61_10785	BG61_35915	GCA_000751215_06010	GCA_000751215_02048	Unannotated protein.	Unannotated protein.	0.439
BG61_10790	BG61_10785	GCA_000751215_06009	GCA_000751215_06010	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein.	0.999
BG61_10790	BG61_16170	GCA_000751215_06009	GCA_000751215_02714	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.696
BG61_10790	BG61_18020	GCA_000751215_06009	GCA_000751215_05991	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein.	0.832
BG61_10790	BG61_18805	GCA_000751215_06009	GCA_000751215_04238	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein.	0.763
BG61_10790	BG61_32760	GCA_000751215_06009	GCA_000751215_02540	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein.	0.763
BG61_10790	BG61_32810	GCA_000751215_06009	GCA_000751215_02530	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein.	0.763
BG61_10790	BG61_35915	GCA_000751215_06009	GCA_000751215_02048	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein.	0.763
BG61_10790	cpsB	GCA_000751215_06009	GCA_000751215_00695	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.696
BG61_10790	cpsB-2	GCA_000751215_06009	GCA_000751215_02687	Unannotated protein; Belongs to the PEP-utilizing enzyme family.	Unannotated protein; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.696
BG61_16170	BG61_02895	GCA_000751215_02714	GCA_000751215_05400	Unannotated protein; Belongs to the mannose-6-phosphate isomerase type 2 family.	Unannotated protein; Belongs to the glycosyl hydrolase 26 family.	0.481

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Network Stats

number of nodes:

11

number of edges:

42

average node degree:

7.64

avg. local clustering coefficient:

0.803

expected number of edges:

11

PPI enrichment p-value:

3.1e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005976

Polysaccharide metabolic process

8 of 71

1.73

3.34

4.03e-10

GO:0000271

Polysaccharide biosynthetic process

6 of 65

1.65

2.35

7.59e-07

GO:0016051

Carbohydrate biosynthetic process

7 of 97

1.54

2.32

1.40e-07

GO:0033692

Cellular polysaccharide biosynthetic process

5 of 47

1.71

2.12

9.80e-06

GO:0005975

Carbohydrate metabolic process

9 of 237

1.26

1.78

3.28e-08

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008767

UDP-galactopyranose mutase activity

2 of 2

2.68

0.93

0.0210

GO:0016740

Transferase activity

8 of 832

0.66

0.43

0.0210

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5129

O-Antigen nucleotide sugar biosynthesis, and Glycosyl transferases group 1

8 of 28

2.14

5.64

4.67e-14

CL:5130

O-Antigen nucleotide sugar biosynthesis

7 of 23

2.16

5.09

3.32e-12

CL:5119

Amino sugar and nucleotide sugar metabolism, and Polysaccharide biosynthetic process

10 of 83

1.76

4.43

3.57e-15

CL:5117

Amino sugar and nucleotide sugar metabolism, and Polysaccharide biosynthetic process

11 of 101

1.72

4.4

2.67e-16

CL:5158

Mannose-6-phosphate isomerase, and NAD dependent epimerase/dehydratase family

3 of 6

2.38

2.29

4.59e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00541

O-Antigen nucleotide sugar biosynthesis

5 of 44

1.74

2.31

3.15e-06

map00520

Amino sugar and nucleotide sugar metabolism

4 of 68

1.45

1.3

0.00062

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0548

Nucleotidyltransferase

3 of 60

1.38

0.69

0.0329

KW-0808

Transferase

7 of 695

0.68

0.41

0.0329

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