STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TERF2IPTERF2 interacting protein. (400 aa)    
Predicted Functional Partners:
POT1
Protection of telomeres 1.
    
 0.998
TINF2
TERF1 interacting nuclear factor 2.
    
 0.998
ACD
ACD shelterin complex subunit and telomerase recruitment factor.
    
 0.997
TERF2
Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
   
 0.997
TERF1
Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
    
 0.994
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
    
 0.967
DCLRE1B
DNA cross-link repair 1B.
    
 
 0.949
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.935
SLX4
Uncharacterized protein.
    
 
 0.893
RAD50
Zinc-hook domain-containing protein.
    
 0.885
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.