STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NUMBLNUMB like endocytic adaptor protein. (602 aa)    
Predicted Functional Partners:
NUMB
NUMB endocytic adaptor protein.
  
 
0.985
NOTCH1
Notch receptor 1.
   
 0.975
NOTCH3
Notch receptor 3.
   
 0.950
NOTCH2
Notch receptor 2.
   
 0.947
NOTCH4
Notch receptor 4.
    
 0.945
ITCH
E3 ubiquitin-protein ligase.
    
 0.910
LNX1
Ligand of numb-protein X 1.
   
 
 0.844
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.795
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 
 0.757
ENSCSAP00000015592
Adaptin_N domain-containing protein.
    
 0.740
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.