| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FZD4 | FZD5 | ENSCSAP00000014421 | ENSCSAP00000018291 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.600 |
| FZD4 | LRP5 | ENSCSAP00000014421 | ENSCSAP00000005238 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | LDL receptor related protein 5. | 0.994 |
| FZD4 | LRP6 | ENSCSAP00000014421 | ENSCSAP00000004889 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.990 |
| FZD4 | WNT3 | ENSCSAP00000014421 | ENSCSAP00000000117 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.956 |
| FZD4 | WNT3A | ENSCSAP00000014421 | ENSCSAP00000012510 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.982 |
| FZD5 | FZD4 | ENSCSAP00000018291 | ENSCSAP00000014421 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.600 |
| FZD5 | FZD7 | ENSCSAP00000018291 | ENSCSAP00000018288 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.935 |
| FZD5 | GPC3 | ENSCSAP00000018291 | ENSCSAP00000004068 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | 0.544 |
| FZD5 | LRP5 | ENSCSAP00000018291 | ENSCSAP00000005238 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | LDL receptor related protein 5. | 0.997 |
| FZD5 | LRP6 | ENSCSAP00000018291 | ENSCSAP00000004889 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.998 |
| FZD5 | WNT3 | ENSCSAP00000018291 | ENSCSAP00000000117 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.968 |
| FZD5 | WNT3A | ENSCSAP00000018291 | ENSCSAP00000012510 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.986 |
| FZD7 | FZD5 | ENSCSAP00000018288 | ENSCSAP00000018291 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.935 |
| FZD7 | LRP5 | ENSCSAP00000018288 | ENSCSAP00000005238 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | LDL receptor related protein 5. | 0.995 |
| FZD7 | LRP6 | ENSCSAP00000018288 | ENSCSAP00000004889 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.996 |
| FZD7 | WNT3 | ENSCSAP00000018288 | ENSCSAP00000000117 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.962 |
| FZD7 | WNT3A | ENSCSAP00000018288 | ENSCSAP00000012510 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.958 |
| GPC3 | FZD5 | ENSCSAP00000004068 | ENSCSAP00000018291 | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.544 |
| GPC3 | NOTUM | ENSCSAP00000004068 | ENSCSAP00000015838 | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Notum, palmitoleoyl-protein carboxylesterase. | 0.826 |
| GPC3 | WNT3 | ENSCSAP00000004068 | ENSCSAP00000000117 | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.929 |
