| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADI1 | BHMT | ENSCSAP00000003223 | ENSCSAP00000011339 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. | 0.457 |
| ADI1 | MTR | ENSCSAP00000003223 | ENSCSAP00000005947 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.457 |
| ADI1 | TAT | ENSCSAP00000003223 | ENSCSAP00000000628 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.947 |
| BHMT | ADI1 | ENSCSAP00000011339 | ENSCSAP00000003223 | Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | 0.457 |
| BHMT | MAT1A | ENSCSAP00000011339 | ENSCSAP00000005644 | Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.963 |
| BHMT | MAT2A | ENSCSAP00000011339 | ENSCSAP00000012240 | Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.963 |
| BHMT | MTR | ENSCSAP00000011339 | ENSCSAP00000005947 | Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.945 |
| BHMT | TAT | ENSCSAP00000011339 | ENSCSAP00000000628 | Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.935 |
| GOT1 | GOT1L1 | ENSCSAP00000002030 | ENSCSAP00000011600 | Aspartate aminotransferase. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.920 |
| GOT1 | GOT2 | ENSCSAP00000002030 | ENSCSAP00000001022 | Aspartate aminotransferase. | Aspartate aminotransferase. | 0.984 |
| GOT1 | HPD | ENSCSAP00000002030 | ENSCSAP00000015853 | Aspartate aminotransferase. | 4-hydroxyphenylpyruvate dioxygenase. | 0.953 |
| GOT1 | MAT1A | ENSCSAP00000002030 | ENSCSAP00000005644 | Aspartate aminotransferase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.528 |
| GOT1 | MAT2A | ENSCSAP00000002030 | ENSCSAP00000012240 | Aspartate aminotransferase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.544 |
| GOT1 | PAH | ENSCSAP00000002030 | ENSCSAP00000014758 | Aspartate aminotransferase. | Phenylalanine hydroxylase. | 0.930 |
| GOT1 | TAT | ENSCSAP00000002030 | ENSCSAP00000000628 | Aspartate aminotransferase. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.956 |
| GOT1L1 | GOT1 | ENSCSAP00000011600 | ENSCSAP00000002030 | Glutamic-oxaloacetic transaminase 1 like 1. | Aspartate aminotransferase. | 0.920 |
| GOT1L1 | GOT2 | ENSCSAP00000011600 | ENSCSAP00000001022 | Glutamic-oxaloacetic transaminase 1 like 1. | Aspartate aminotransferase. | 0.969 |
| GOT1L1 | HPD | ENSCSAP00000011600 | ENSCSAP00000015853 | Glutamic-oxaloacetic transaminase 1 like 1. | 4-hydroxyphenylpyruvate dioxygenase. | 0.950 |
| GOT1L1 | MAT1A | ENSCSAP00000011600 | ENSCSAP00000005644 | Glutamic-oxaloacetic transaminase 1 like 1. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.527 |
| GOT1L1 | MAT2A | ENSCSAP00000011600 | ENSCSAP00000012240 | Glutamic-oxaloacetic transaminase 1 like 1. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.527 |
