Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)    
Predicted Functional Partners:
PTH1R
Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family.
   
 0.997
PTH2R
Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.
   
 0.993
PTH2
Parathyroid hormone 2.
     
 0.961
CASR
Calcium sensing receptor.
      
 0.785
PTHLH
Parathyroid hormone like hormone.
     
 0.774
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
      
 0.716
PNMT
Phenylethanolamine N-methyltransferase.
      
 0.700
CYP27B1
Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 
 0.696
BGLAP
Osteocalcin; Binds strongly to apatite and calcium.
      
 0.677
VDR
Vitamin D receptor.
      
 0.669
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.