Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa)    
Predicted Functional Partners:
RPRD1B
Regulation of nuclear pre-mRNA domain containing 1B.
    
 0.973
POLR2G
RNA polymerase II subunit G.
    
 
 0.942
POLR2D
RNA polymerase II subunit D.
    
 
 0.942
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.918
MYZAP
Myocardial zonula adherens protein.
    
   0.909
RPRD1A
Regulation of nuclear pre-mRNA domain containing 1A.
    
 0.873
FANCM
FA complementation group M.
   
 0.864
POLR2M
RNA polymerase II subunit M.
    
  0.863
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.858
DNA2
DNA replication helicase/nuclease 2.
   
 0.808
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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