Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CX3CL1C-X3-C motif chemokine ligand 1. (402 aa)    
Predicted Functional Partners:
CX3CR1
C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.995
CCR5
C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity).
    
 0.939
CCR2
C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.927
CCR8
C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family.
    
 0.916
CCR3
C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 0.900
CCR7
C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.
     
 0.854
CCR1
C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.842
CXCR2
C-X-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.
     
 0.839
CXCR1
C-X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.839
CXCR3
C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.
     
 0.831
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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