| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COMT | CYP1A1 | ENSCSAP00000008134 | ENSCSAP00000010381 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.945 |
| COMT | CYP1B1 | ENSCSAP00000008134 | ENSCSAP00000008414 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.941 |
| COMT | UGT2B4 | ENSCSAP00000008134 | ENSCSAP00000001268 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.929 |
| CYP1A1 | COMT | ENSCSAP00000010381 | ENSCSAP00000008134 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.945 |
| CYP1A1 | CYP1B1 | ENSCSAP00000010381 | ENSCSAP00000008414 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.939 |
| CYP1A1 | CYP2B6 | ENSCSAP00000010381 | ENSCSAP00000014443 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | 0.937 |
| CYP1A1 | CYP2C9 | ENSCSAP00000010381 | ENSCSAP00000002472 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.935 |
| CYP1A1 | CYP2D6 | ENSCSAP00000010381 | ENSCSAP00000001992 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.930 |
| CYP1A1 | CYP2E1 | ENSCSAP00000010381 | ENSCSAP00000002900 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.936 |
| CYP1A1 | CYP3A4 | ENSCSAP00000010381 | ENSCSAP00000013846 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 4; Belongs to the cytochrome P450 family. | 0.963 |
| CYP1A1 | CYP3A5 | ENSCSAP00000010381 | ENSCSAP00000013832 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 5. | 0.954 |
| CYP1A1 | ENSCSAP00000007181 | ENSCSAP00000010381 | ENSCSAP00000007181 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.916 |
| CYP1A1 | UGT2B4 | ENSCSAP00000010381 | ENSCSAP00000001268 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.942 |
| CYP1B1 | COMT | ENSCSAP00000008414 | ENSCSAP00000008134 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.941 |
| CYP1B1 | CYP1A1 | ENSCSAP00000008414 | ENSCSAP00000010381 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.939 |
| CYP1B1 | CYP2B6 | ENSCSAP00000008414 | ENSCSAP00000014443 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | 0.926 |
| CYP1B1 | CYP3A4 | ENSCSAP00000008414 | ENSCSAP00000013846 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 4; Belongs to the cytochrome P450 family. | 0.527 |
| CYP1B1 | CYP3A5 | ENSCSAP00000008414 | ENSCSAP00000013832 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 5. | 0.437 |
| CYP1B1 | UGT2B4 | ENSCSAP00000008414 | ENSCSAP00000001268 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.940 |
| CYP2B6 | CYP1A1 | ENSCSAP00000014443 | ENSCSAP00000010381 | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.937 |