Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa)    
Predicted Functional Partners:
SYVN1
Synoviolin 1.
   
 0.960
AMFR
Autocrine motility factor receptor.
   
 
 0.927
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 0.803
UBA6
Ubiquitin like modifier activating enzyme 6.
      
 0.797
ZNF622
Zinc finger protein 622.
      
 0.754
DNAJB9
DnaJ heat shock protein family (Hsp40) member B9.
   
  
 0.732
CTH
Cystathionine gamma-lyase.
      
 0.689
ATF4
Activating transcription factor 4.
   
 
 0.687
XBP1
X-box binding protein 1.
   
 
 0.676
EDEM1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
  
 0.631
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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