Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
PANX2Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (550 aa)    
Predicted Functional Partners:
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
     
 0.913
SLC18B1
Solute carrier family 18 member B1.
      
 0.609
POMGNT2
Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-).
      
 0.609
ANO8
Anoctamin.
      
 0.555
CALHM1
Calcium homeostasis modulator 1.
      
 0.536
RIPK4
Receptor interacting serine/threonine kinase 4.
      
 0.482
FICD
FIC domain containing.
      
 0.481
PTCHD1
Patched domain containing 1.
      
 0.461
HOXC6
Homeobox C6.
      
 0.414
GJA5
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.414
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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