STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RHBDF2Rhomboid 5 homolog 2. (856 aa)    
Predicted Functional Partners:
ADAM17
ADAM metallopeptidase domain 17.
    
 0.990
FRMD8
FERM domain containing 8.
     
 0.928
RHBDF1
Rhomboid 5 homolog 1.
  
  
 
0.902
ADAM10
ADAM metallopeptidase domain 10.
    
 0.594
MEGF11
Multiple EGF like domains 11.
   
  
 0.565
STARD3
StAR related lipid transfer domain containing 3.
    
   0.558
PHLDB1
Pleckstrin homology like domain family B member 1.
   
  
 0.536
WSCD2
WSC domain containing 2.
   
  
 0.525
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
    
 
 0.520
D2HGDH
D-2-hydroxyglutarate dehydrogenase.
      
 0.514
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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