Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (326 aa)    
Predicted Functional Partners:
FBXW11
F-box and WD repeat domain containing 11.
      
 0.708
BICC1
BicC family RNA binding protein 1.
      
 0.673
PUF60
Poly(U) binding splicing factor 60.
      
 0.672
TRIM71
Tripartite motif containing 71.
    
 
 0.614
SCRIB
Scribble planar cell polarity protein.
    
 0.581
LRRC1
Leucine rich repeat containing 1.
    
 0.581
COPS7B
COP9 signalosome subunit 7B.
      
 0.576
CPEB1
Uncharacterized protein.
      
 0.573
DDX5
DEAD-box helicase 5; Belongs to the DEAD box helicase family.
   
 
 0.556
EFNB3
Ephrin B3; Belongs to the ephrin family.
   
  
 0.551
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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