Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMFRAutocrine motility factor receptor. (643 aa)    
Predicted Functional Partners:
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.992
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
    
 0.985
UBC
Uncharacterized protein.
    
 0.973
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.972
RPS27A
Ubiquitin-like domain-containing protein.
    
 0.972
ENSCSAP00000018444
Ubiquitin-like domain-containing protein.
    
  0.972
UBE2G2
Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.971
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 0.968
INSIG1
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
    
 
 0.966
UBXN1
UBX domain protein 1.
    
 0.965
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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