Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)    
Predicted Functional Partners:
MRAS
Muscle RAS oncogene homolog.
    
 0.981
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.951
RRAS2
RAS related 2.
    
 0.948
RRAS
RAS related.
    
 0.948
KRAS
KRAS proto-oncogene, GTPase.
   
 0.942
HRAS
HRas proto-oncogene, GTPase.
   
 0.942
NRAS
NRAS proto-oncogene, GTPase.
   
 0.942
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.785
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.776
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
 0.665
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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