| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC30 | SLC25A42 | ENSCSAP00000016848 | ENSCSAP00000001541 | Coiled-coil domain containing 30. | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.658 |
| CENPT | SLC25A42 | ENSCSAP00000000313 | ENSCSAP00000001541 | Centromere protein T. | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.733 |
| MCM7 | PCNA | ENSCSAP00000013867 | ENSCSAP00000009557 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.990 |
| MCM7 | RFC3 | ENSCSAP00000013867 | ENSCSAP00000013917 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Replication factor C subunit 3. | 0.899 |
| MCM7 | RRM1 | ENSCSAP00000013867 | ENSCSAP00000000608 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.926 |
| MCM7 | SLC25A42 | ENSCSAP00000013867 | ENSCSAP00000001541 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.599 |
| MCM7 | TYMS | ENSCSAP00000013867 | ENSCSAP00000013647 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Thymidylate synthetase. | 0.616 |
| MRPL58 | SLC25A42 | ENSCSAP00000000987 | ENSCSAP00000001541 | Mitochondrial ribosomal protein L58. | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.705 |
| PCNA | MCM7 | ENSCSAP00000009557 | ENSCSAP00000013867 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.990 |
| PCNA | RFC3 | ENSCSAP00000009557 | ENSCSAP00000013917 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 3. | 0.993 |
| PCNA | RRM1 | ENSCSAP00000009557 | ENSCSAP00000000608 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.892 |
| PCNA | SLC25A42 | ENSCSAP00000009557 | ENSCSAP00000001541 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.774 |
| PCNA | TYMS | ENSCSAP00000009557 | ENSCSAP00000013647 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Thymidylate synthetase. | 0.929 |
| PCNA | UNG | ENSCSAP00000009557 | ENSCSAP00000015196 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.876 |
| PPCS | SLC25A42 | ENSCSAP00000016849 | ENSCSAP00000001541 | Phosphopantothenoylcysteine synthetase. | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.659 |
| RFC3 | MCM7 | ENSCSAP00000013917 | ENSCSAP00000013867 | Replication factor C subunit 3. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.899 |
| RFC3 | PCNA | ENSCSAP00000013917 | ENSCSAP00000009557 | Replication factor C subunit 3. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.993 |
| RFC3 | RRM1 | ENSCSAP00000013917 | ENSCSAP00000000608 | Replication factor C subunit 3. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.543 |
| RFC3 | SLC25A42 | ENSCSAP00000013917 | ENSCSAP00000001541 | Replication factor C subunit 3. | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.690 |
| RFC3 | TYMS | ENSCSAP00000013917 | ENSCSAP00000013647 | Replication factor C subunit 3. | Thymidylate synthetase. | 0.600 |