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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORCS3Sortilin related VPS10 domain containing receptor 3. (956 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
     
 0.920
TACC2
Transforming acidic coiled-coil containing protein 2.
      
 0.645
CRTC1
CREB regulated transcription coactivator 1.
      
 0.639
NGF
Nerve growth factor; Belongs to the NGF-beta family.
    
 
 0.608
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
     
 0.607
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.602
IGF2R
Insulin like growth factor 2 receptor.
    
 0.540
SORT1
Sortilin.
    
 
0.539
CDH8
Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.
   
 
 0.531
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.525
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.