Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MPPED2Metallophosphoesterase domain containing 2. (294 aa)    
Predicted Functional Partners:
NR2F6
Nuclear receptor subfamily 2 group F member 6.
    
 
 0.773
UCK1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
   0.759
UPRT
Uracil phosphoribosyltransferase homolog.
    
   0.756
PHKA1
Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
    
   0.734
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
   0.722
TXNDC9
Thioredoxin domain containing 9.
    
   0.715
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
    
   0.640
ENSCSAP00000001560
Doublecortin domain-containing protein.
      
 0.619
DNAJC24
DnaJ heat shock protein family (Hsp40) member C24.
      
 0.611
PHKG2
Phosphorylase kinase catalytic subunit gamma 2.
    
   0.582
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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