Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CHD9Chromodomain helicase DNA binding protein 9. (2902 aa)    
Predicted Functional Partners:
CHD8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
   
    0.845
CHD7
Chromodomain helicase DNA binding protein 7.
   
    0.844
CTNNB1
Catenin beta 1.
   
 0.707
ZFP90
ZFP90 zinc finger protein.
   
 0.687
HDHD3
Haloacid dehalogenase like hydrolase domain containing 3.
   
  
 0.673
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.665
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 
 0.648
PHF3
PHD finger protein 3.
   
 0.641
SFMBT1
Scm like with four mbt domains 1.
   
 0.585
ARID4B
AT-rich interaction domain 4B.
   
 0.578
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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