Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH3PXD2ASH3 and PX domains 2A. (978 aa)    
Predicted Functional Partners:
ADAM15
ADAM metallopeptidase domain 15.
    
 0.818
WASL
WASP like actin nucleation promoting factor.
   
 0.629
TLE2
TLE family member 2, transcriptional corepressor.
      
 0.616
FAM13B
Family with sequence similarity 13 member B.
      
 0.566
CTTN
Cortactin.
    
 0.560
FRMD8
FERM domain containing 8.
      
 0.556
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
   0.544
HCLS1
Hematopoietic cell-specific Lyn substrate 1.
    
 0.540
SRC
Tyrosine-protein kinase.
    
 0.534
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
     
 0.520
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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