Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)    
Predicted Functional Partners:
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.812
PDE9A
Phosphodiesterase.
    
 
 0.662
CAND2
Cullin associated and neddylation dissociated 2 (putative).
     
 0.624
JAG1
Jagged canonical Notch ligand 1.
    
 0.593
SQSTM1
Sequestosome 1.
   
 
 0.591
GSAP
Gamma-secretase activating protein.
   
 
 0.591
NBR1
NBR1 autophagy cargo receptor.
   
 
 0.591
TTC26
Tetratricopeptide repeat domain 26.
      
 0.576
EPN3
Epsin 3.
    
 
 0.556
ENTHD1
ENTH domain containing 1.
    
 
 0.551
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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