STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK3Tyrosine-protein kinase. (1069 aa)    
Predicted Functional Partners:
IL2RG
Fibronectin type-III domain-containing protein.
   
 0.998
STAT3
Signal transducer and activator of transcription.
   
 0.995
JAK1
Tyrosine-protein kinase.
   
0.995
STAT6
Signal transducer and activator of transcription.
   
 0.992
IL2RB
Interleukin 2 receptor subunit beta.
   
 0.992
STAT5A
Signal transducer and activator of transcription.
   
 0.990
SOCS1
Suppressor of cytokine signaling 1.
    
 0.990
SOCS3
Suppressor of cytokine signaling 3.
   
 0.990
STAT5B
Signal transducer and activator of transcription.
   
 0.988
IFNGR2
Interferon gamma receptor 2.
    
 0.986
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.