| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD4 | CXCR5 | ENSCSAP00000006497 | ENSCSAP00000015483 | CD4 molecule. | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. | 0.887 |
| CD4 | IFNG | ENSCSAP00000006497 | ENSCSAP00000000682 | CD4 molecule. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.955 |
| CD4 | MYB | ENSCSAP00000006497 | ENSCSAP00000012868 | CD4 molecule. | MYB proto-oncogene, transcription factor. | 0.411 |
| CD4 | MYD88 | ENSCSAP00000006497 | ENSCSAP00000010525 | CD4 molecule. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.839 |
| CD4 | RAG1 | ENSCSAP00000006497 | ENSCSAP00000001800 | CD4 molecule. | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.748 |
| CD4 | RAG2 | ENSCSAP00000006497 | ENSCSAP00000018723 | CD4 molecule. | Recombination activating 2. | 0.830 |
| CD4 | STAT1 | ENSCSAP00000006497 | ENSCSAP00000008380 | CD4 molecule. | Signal transducer and activator of transcription. | 0.853 |
| CXCR5 | CD4 | ENSCSAP00000015483 | ENSCSAP00000006497 | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. | CD4 molecule. | 0.887 |
| CXCR5 | IFNG | ENSCSAP00000015483 | ENSCSAP00000000682 | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.670 |
| CXCR5 | RAG1 | ENSCSAP00000015483 | ENSCSAP00000001800 | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.671 |
| CXCR5 | RAG2 | ENSCSAP00000015483 | ENSCSAP00000018723 | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. | Recombination activating 2. | 0.405 |
| IFNG | CD4 | ENSCSAP00000000682 | ENSCSAP00000006497 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | CD4 molecule. | 0.955 |
| IFNG | CXCR5 | ENSCSAP00000000682 | ENSCSAP00000015483 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. | 0.670 |
| IFNG | MYD88 | ENSCSAP00000000682 | ENSCSAP00000010525 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.735 |
| IFNG | RAG1 | ENSCSAP00000000682 | ENSCSAP00000001800 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.686 |
| IFNG | RAG2 | ENSCSAP00000000682 | ENSCSAP00000018723 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Recombination activating 2. | 0.521 |
| IFNG | STAT1 | ENSCSAP00000000682 | ENSCSAP00000008380 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Signal transducer and activator of transcription. | 0.925 |
| IFNG | ZMYM2 | ENSCSAP00000000682 | ENSCSAP00000014124 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Zinc finger MYM-type containing 2. | 0.402 |
| IFNG | ZMYM3 | ENSCSAP00000000682 | ENSCSAP00000007606 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Zinc finger MYM-type containing 3. | 0.402 |
| KPNA1 | RAG1 | ENSCSAP00000003660 | ENSCSAP00000001800 | Importin subunit alpha; Functions in nuclear protein import. | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.812 |
