Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DDB2Damage specific DNA binding protein 2. (427 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.998
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.990
RBX1
Ring-box 1.
    
 0.989
COPS2
COP9 signalosome subunit 2.
    
 0.986
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.986
XPC
XPC complex subunit, DNA damage recognition and repair factor.
   
 0.981
COPS3
COP9 signalosome subunit 3.
    
 0.977
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
0.977
COPS4
COP9 signalosome subunit 4.
    
 0.976
COP1
COP1 E3 ubiquitin ligase.
    
 0.975
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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