STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MADDMAP kinase activating death domain. (1604 aa)    
Predicted Functional Partners:
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.807
SYT6
Synaptotagmin 6.
    
   0.767
DENND1A
DENN domain containing 1A.
    
 
 0.732
RAB27A
RAB27A, member RAS oncogene family.
     
 0.678
RAB27B
RAB27B, member RAS oncogene family.
     
 0.678
DMXL2
Dmx like 2.
    
 
 0.672
RAB35
RAB35, member RAS oncogene family.
      
 0.641
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
 0.639
DENND5A
DENN domain containing 5A.
    
 
 0.600
DENND5B
DENN domain containing 5B.
    
 
 0.588
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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