STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PYCARDPYD and CARD domain containing. (195 aa)    
Predicted Functional Partners:
CASP1
Caspase 1; Belongs to the peptidase C14A family.
   
 0.999
AIM2
Absent in melanoma 2.
    
 0.998
ENSCSAP00000014978
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.997
MEFV
MEFV innate immuity regulator, pyrin.
    
 0.994
NLRP3
NLR family pyrin domain containing 3.
   
 0.992
NLRC4
NLR family CARD domain containing 4.
    
 0.992
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
 0.990
IL1B
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
   
 
 0.982
NLRP1
NLR family pyrin domain containing 1.
   
 0.979
NLRP7
NLR family pyrin domain containing 7.
   
 0.975
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.