Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PRSS36Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family. (854 aa)    
Predicted Functional Partners:
AQP6
Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.747
ATP2A1
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 
 0.710
CPB1
Carboxypeptidase B1.
   
 
 0.695
DEF8
Differentially expressed in FDCP 8 homolog.
      
 0.678
SCNN1B
Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.630
KMT2C
Lysine methyltransferase 2C.
   
  
 0.610
ABI3
ABI family member 3.
      
 0.609
TREML2
Triggering receptor expressed on myeloid cells like 2.
     
 0.578
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3.
   
  
 0.578
SPINT2
Serine peptidase inhibitor, Kunitz type 2.
    
 0.552
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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