STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MEI1Meiotic double-stranded break formation protein 1. (1327 aa)    
Predicted Functional Partners:
REC114
REC114 meiotic recombination protein.
      
 0.706
ANKRD31
RAMA domain-containing protein.
    
 
 0.702
M1AP
Meiosis 1 associated protein.
      
 0.668
KATNBL1
Katanin regulatory subunit B1 like 1.
      
 0.667
HORMAD1
HORMA domain containing 1.
      
 0.664
KATNB1
Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...]
      
 0.615
SPO11
SPO11 initiator of meiotic double stranded breaks.
      
 0.604
SMC1B
Structural maintenance of chromosomes protein.
      
 0.584
PMPCA
Peptidase, mitochondrial processing alpha subunit; Belongs to the peptidase M16 family.
    
   0.583
SYCP1
Synaptonemal complex protein 1.
      
 0.582
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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