| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD14 | CSF1R | ENSCSAP00000008926 | ENSCSAP00000007884 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.616 |
| CD14 | SPI1 | ENSCSAP00000008926 | ENSCSAP00000002067 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] | Spi-1 proto-oncogene. | 0.911 |
| CSF1R | CD14 | ENSCSAP00000007884 | ENSCSAP00000008926 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] | 0.616 |
| CSF1R | ITGAM | ENSCSAP00000007884 | ENSCSAP00000002002 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Integrin subunit alpha M; Belongs to the integrin alpha chain family. | 0.591 |
| CSF1R | LOC103247163 | ENSCSAP00000007884 | ENSCSAP00000014157 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Uncharacterized protein. | 0.470 |
| CSF1R | RUNX1 | ENSCSAP00000007884 | ENSCSAP00000004965 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.957 |
| CSF1R | SPI1 | ENSCSAP00000007884 | ENSCSAP00000002067 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Spi-1 proto-oncogene. | 0.961 |
| FLT3 | GATA2 | ENSCSAP00000013992 | ENSCSAP00000004867 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | GATA binding protein 2. | 0.410 |
| FLT3 | ITGAM | ENSCSAP00000013992 | ENSCSAP00000002002 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Integrin subunit alpha M; Belongs to the integrin alpha chain family. | 0.487 |
| FLT3 | RARA | ENSCSAP00000013992 | ENSCSAP00000015260 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Retinoic acid receptor alpha. | 0.467 |
| FLT3 | RUNX1 | ENSCSAP00000013992 | ENSCSAP00000004965 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.543 |
| FLT3 | RUNX1T1 | ENSCSAP00000013992 | ENSCSAP00000008971 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | RUNX1 partner transcriptional co-repressor 1. | 0.462 |
| FLT3 | SPI1 | ENSCSAP00000013992 | ENSCSAP00000002067 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Spi-1 proto-oncogene. | 0.947 |
| GATA2 | FLT3 | ENSCSAP00000004867 | ENSCSAP00000013992 | GATA binding protein 2. | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.410 |
| GATA2 | RUNX1 | ENSCSAP00000004867 | ENSCSAP00000004965 | GATA binding protein 2. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.819 |
| GATA2 | SPI1 | ENSCSAP00000004867 | ENSCSAP00000002067 | GATA binding protein 2. | Spi-1 proto-oncogene. | 0.908 |
| ITGAM | CSF1R | ENSCSAP00000002002 | ENSCSAP00000007884 | Integrin subunit alpha M; Belongs to the integrin alpha chain family. | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.591 |
| ITGAM | FLT3 | ENSCSAP00000002002 | ENSCSAP00000013992 | Integrin subunit alpha M; Belongs to the integrin alpha chain family. | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.487 |
| ITGAM | LOC103247163 | ENSCSAP00000002002 | ENSCSAP00000014157 | Integrin subunit alpha M; Belongs to the integrin alpha chain family. | Uncharacterized protein. | 0.578 |
| ITGAM | SPI1 | ENSCSAP00000002002 | ENSCSAP00000002067 | Integrin subunit alpha M; Belongs to the integrin alpha chain family. | Spi-1 proto-oncogene. | 0.942 |
