STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BOKBCL2 family apoptosis regulator BOK. (212 aa)    
Predicted Functional Partners:
PMAIP1
Phorbol-12-myristate-13-acetate-induced protein 1.
    
 0.698
ENSCSAP00000018835
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    
 0.682
HRK
Activator of apoptosis harakiri; Promotes apoptosis.
    
 
 0.681
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
    
 0.678
MCL1
MCL1 apoptosis regulator, BCL2 family member.
    
 
 0.671
BAD
BCL2 associated agonist of cell death.
   
 0.654
BCL2L11
BCL2 like 11.
    
 0.639
TESPA1
Thymocyte expressed, positive selection associated 1.
    
   0.585
BNIP3L
BCL2 interacting protein 3 like.
    
 
 0.579
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 
 0.573
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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