Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSH2DHematopoietic SH2 domain containing. (352 aa)    
Predicted Functional Partners:
TNK2
Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 
 0.642
APOBEC3H
Apolipoprotein B mRNA editing enzyme catalytic subunit 3H.
      
 0.522
GRAP
GRB2 related adaptor protein.
      
 0.478
SPAG5
Sperm associated antigen 5.
      
 0.473
SIGLEC1
Sialic acid binding Ig like lectin 1.
   
  
 0.456
TNK1
Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 
 0.425
CRK
CRK proto-oncogene, adaptor protein.
    
 
 0.419
KIFC1
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.409
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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