VMP1 protein (Chlorocebus sabaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

VMP1

Vacuole membrane protein 1. (406 aa)

Predicted Functional Partners:

BECN1

0.960

ATG13

0.945

BECN2

0.941

TP53INP2

0.913

TMEM64

0.871

TMEM41B

0.749

TMEM41A

0.684

ATG7

0.647

AUTS2

0.633

TBC1D5

0.611

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG13	ATG7	ENSCSAP00000001989	ENSCSAP00000006129	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.794
ATG13	BECN1	ENSCSAP00000001989	ENSCSAP00000014702	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Beclin 1.	0.993
ATG13	BECN2	ENSCSAP00000001989	ENSCSAP00000018881	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Beclin 2.	0.985
ATG13	TBC1D5	ENSCSAP00000001989	ENSCSAP00000006174	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	TBC1 domain family member 5.	0.445
ATG13	VMP1	ENSCSAP00000001989	ENSCSAP00000002188	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Vacuole membrane protein 1.	0.945
ATG7	ATG13	ENSCSAP00000006129	ENSCSAP00000001989	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.794
ATG7	BECN1	ENSCSAP00000006129	ENSCSAP00000014702	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Beclin 1.	0.901
ATG7	BECN2	ENSCSAP00000006129	ENSCSAP00000018881	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Beclin 2.	0.711
ATG7	TMEM41A	ENSCSAP00000006129	ENSCSAP00000010134	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Transmembrane protein 41A.	0.420
ATG7	VMP1	ENSCSAP00000006129	ENSCSAP00000002188	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Vacuole membrane protein 1.	0.647
AUTS2	VMP1	ENSCSAP00000014282	ENSCSAP00000002188	Activator of transcription and developmental regulator AUTS2.	Vacuole membrane protein 1.	0.633
BECN1	ATG13	ENSCSAP00000014702	ENSCSAP00000001989	Beclin 1.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.993
BECN1	ATG7	ENSCSAP00000014702	ENSCSAP00000006129	Beclin 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.901
BECN1	BECN2	ENSCSAP00000014702	ENSCSAP00000018881	Beclin 1.	Beclin 2.	0.902
BECN1	VMP1	ENSCSAP00000014702	ENSCSAP00000002188	Beclin 1.	Vacuole membrane protein 1.	0.960
BECN2	ATG13	ENSCSAP00000018881	ENSCSAP00000001989	Beclin 2.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.985
BECN2	ATG7	ENSCSAP00000018881	ENSCSAP00000006129	Beclin 2.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.711
BECN2	BECN1	ENSCSAP00000018881	ENSCSAP00000014702	Beclin 2.	Beclin 1.	0.902
BECN2	VMP1	ENSCSAP00000018881	ENSCSAP00000002188	Beclin 2.	Vacuole membrane protein 1.	0.941
TBC1D5	ATG13	ENSCSAP00000006174	ENSCSAP00000001989	TBC1 domain family member 5.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.445

page 1 of 3

Server load: low (24%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About