Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COL8A1Collagen type VIII alpha 1 chain. (746 aa)    
Predicted Functional Partners:
COL8A2
Collagen type VIII alpha 2 chain.
   
  0.922
THBS4
Thrombospondin 4.
   
 0.632
COL6A2
Collagen type VI alpha 2 chain.
  
0.631
COL6A1
Uncharacterized protein.
  
0.630
RIPK4
Receptor interacting serine/threonine kinase 4.
    
 0.601
ACP5
Tartrate-resistant acid phosphatase type 5.
      
 0.556
PFDN4
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.
    
   0.549
P3H1
Prolyl 3-hydroxylase 1.
   
 0.546
MMP25
Matrix metallopeptidase 25.
    
 0.542
ITGA6
Integrin subunit alpha 6; Belongs to the integrin alpha chain family.
    
 0.540
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.