STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DTX4Deltex E3 ubiquitin ligase 4. (619 aa)    
Predicted Functional Partners:
NOTCH1
Notch receptor 1.
    
 0.752
TBK1
TANK binding kinase 1.
    
 0.700
NLRP4
NLR family pyrin domain containing 4.
    
 0.695
NOTCH2
Notch receptor 2.
     
 0.664
NOTCH4
Notch receptor 4.
     
 0.661
NOTCH3
Notch receptor 3.
     
 0.660
ITCH
E3 ubiquitin-protein ligase.
     
 0.506
DIXDC1
DIX domain containing 1.
      
 0.466
UPK2
Uroplakin 2.
     
 0.463
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.424
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.