Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BRD4Bromodomain containing 4. (1365 aa)    
Predicted Functional Partners:
BRD3
Bromodomain containing 3.
   
 
 0.987
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
   
 
 0.976
CCNT1
Cyclin T1; Belongs to the cyclin family.
   
 
 0.969
BRD2
Bromodomain containing 2.
   
 
 0.967
NSD3
Nuclear receptor binding SET domain protein 3.
   
 0.952
JMJD6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
    
 
 0.935
CHD4
Uncharacterized protein.
   
 
 0.935
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 
 0.930
ENSCSAP00000003179
Uncharacterized protein.
   
 
 0.927
ATAD5
ATPase family AAA domain containing 5.
   
 
 0.923
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.