STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NOTCH3Notch receptor 3. (1980 aa)    
Predicted Functional Partners:
JAG2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.997
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.997
JAG1
Jagged canonical Notch ligand 1.
   
0.996
MAML1
Mastermind like transcriptional coactivator 1.
   
 0.995
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.995
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.992
MAML2
Mastermind like transcriptional coactivator 2.
    
 0.981
NUMB
NUMB endocytic adaptor protein.
   
 0.962
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
    
 0.957
DLL3
Delta like canonical Notch ligand 3.
    
0.951
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.