STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SORBS1Sorbin and SH3 domain containing 1. (1793 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.992
FLOT1
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
  0.978
FLOT2
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
 0.940
AFDN
Afadin, adherens junction formation factor.
    
 0.925
CBL
Cbl proto-oncogene.
    
 
 0.873
ITGA1
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
 
 0.806
SORBS3
Sorbin and SH3 domain containing 3.
    
 0.791
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
     
 0.755
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
   
 0.661
ABL1
Tyrosine-protein kinase.
    
 0.632
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.