| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARRB2 | MAP2K1 | ENSCSAP00000009268 | ENSCSAP00000009363 | Arrestin beta 2. | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | 0.594 |
| ARRB2 | MAP2K2 | ENSCSAP00000009268 | ENSCSAP00000006991 | Arrestin beta 2. | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | 0.440 |
| ARRB2 | MAPK1 | ENSCSAP00000009268 | ENSCSAP00000009828 | Arrestin beta 2. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.985 |
| ARRB2 | MAPK3 | ENSCSAP00000009268 | ENSCSAP00000002490 | Arrestin beta 2. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.988 |
| DUSP1 | MAPK1 | ENSCSAP00000005848 | ENSCSAP00000009828 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.990 |
| DUSP1 | MAPK3 | ENSCSAP00000005848 | ENSCSAP00000002490 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.990 |
| MAP2K1 | ARRB2 | ENSCSAP00000009363 | ENSCSAP00000009268 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Arrestin beta 2. | 0.594 |
| MAP2K1 | MAP2K2 | ENSCSAP00000009363 | ENSCSAP00000006991 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | 0.999 |
| MAP2K1 | MAPK1 | ENSCSAP00000009363 | ENSCSAP00000009828 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.997 |
| MAP2K1 | MAPK3 | ENSCSAP00000009363 | ENSCSAP00000002490 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.998 |
| MAP2K1 | TP53 | ENSCSAP00000009363 | ENSCSAP00000007551 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.439 |
| MAP2K2 | ARRB2 | ENSCSAP00000006991 | ENSCSAP00000009268 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | Arrestin beta 2. | 0.440 |
| MAP2K2 | MAP2K1 | ENSCSAP00000006991 | ENSCSAP00000009363 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | 0.999 |
| MAP2K2 | MAPK1 | ENSCSAP00000006991 | ENSCSAP00000009828 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.995 |
| MAP2K2 | MAPK3 | ENSCSAP00000006991 | ENSCSAP00000002490 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.992 |
| MAPK1 | ARRB2 | ENSCSAP00000009828 | ENSCSAP00000009268 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Arrestin beta 2. | 0.985 |
| MAPK1 | DUSP1 | ENSCSAP00000009828 | ENSCSAP00000005848 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.990 |
| MAPK1 | MAP2K1 | ENSCSAP00000009828 | ENSCSAP00000009363 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | 0.997 |
| MAPK1 | MAP2K2 | ENSCSAP00000009828 | ENSCSAP00000006991 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | 0.995 |
| MAPK1 | MAPK3 | ENSCSAP00000009828 | ENSCSAP00000002490 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.999 |
