STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLCE1Phosphoinositide phospholipase C. (2317 aa)    
Predicted Functional Partners:
INPP5A
Inositol polyphosphate-5-phosphatase A.
     
 0.966
HRAS
HRas proto-oncogene, GTPase.
    
 0.928
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.928
KRAS
KRAS proto-oncogene, GTPase.
    
 0.917
NRAS
NRAS proto-oncogene, GTPase.
    
 0.917
PRKCA
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 0.913
RAP1B
Uncharacterized protein.
    
 0.913
IPMK
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.913
PRKCB
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 0.912
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
   
 
 0.911
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.