Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
CBLBCbl proto-oncogene B. (982 aa)    
Predicted Functional Partners:
EGFR
Receptor protein-tyrosine kinase.
    
 0.995
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 0.990
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.986
ZAP70
Tyrosine-protein kinase.
    
 0.986
GRB2
Growth factor receptor bound protein 2.
    
 0.985
SYK
Tyrosine-protein kinase.
    
 0.984
CBL
Cbl proto-oncogene.
  
0.978
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.976
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.976
RAPGEF1
Rap guanine nucleotide exchange factor 1.
   
 0.968
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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