| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COMT | CYP1A1 | ENSCSAP00000008134 | ENSCSAP00000010381 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.945 |
| COMT | CYP1B1 | ENSCSAP00000008134 | ENSCSAP00000008414 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.949 |
| COMT | ENSCSAP00000000542 | ENSCSAP00000008134 | ENSCSAP00000000542 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Uncharacterized protein. | 0.941 |
| COMT | ENSCSAP00000002604 | ENSCSAP00000008134 | ENSCSAP00000002604 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.945 |
| CYP1A1 | COMT | ENSCSAP00000010381 | ENSCSAP00000008134 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.945 |
| CYP1A1 | CYP1B1 | ENSCSAP00000010381 | ENSCSAP00000008414 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.940 |
| CYP1A1 | CYP2B6 | ENSCSAP00000010381 | ENSCSAP00000014443 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | 0.933 |
| CYP1A1 | CYP2C8 | ENSCSAP00000010381 | ENSCSAP00000002470 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. | 0.931 |
| CYP1A1 | CYP2D6 | ENSCSAP00000010381 | ENSCSAP00000001992 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.935 |
| CYP1A1 | CYP2E1 | ENSCSAP00000010381 | ENSCSAP00000002900 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.938 |
| CYP1A1 | CYP3A5 | ENSCSAP00000010381 | ENSCSAP00000013832 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 5. | 0.956 |
| CYP1A1 | ENSCSAP00000000542 | ENSCSAP00000010381 | ENSCSAP00000000542 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.944 |
| CYP1A1 | ENSCSAP00000002604 | ENSCSAP00000010381 | ENSCSAP00000002604 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.962 |
| CYP1A1 | SULT1E1 | ENSCSAP00000010381 | ENSCSAP00000001258 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.920 |
| CYP1B1 | COMT | ENSCSAP00000008414 | ENSCSAP00000008134 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.949 |
| CYP1B1 | CYP1A1 | ENSCSAP00000008414 | ENSCSAP00000010381 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.940 |
| CYP1B1 | CYP2B6 | ENSCSAP00000008414 | ENSCSAP00000014443 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | 0.929 |
| CYP1B1 | CYP2E1 | ENSCSAP00000008414 | ENSCSAP00000002900 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.406 |
| CYP1B1 | CYP3A5 | ENSCSAP00000008414 | ENSCSAP00000013832 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 5. | 0.481 |
| CYP1B1 | ENSCSAP00000000542 | ENSCSAP00000008414 | ENSCSAP00000000542 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.959 |