Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CHRNGCholinergic receptor nicotinic gamma subunit. (516 aa)    
Predicted Functional Partners:
CHRND
Cholinergic receptor nicotinic delta subunit.
   
 0.870
CHRNA1
Neur_chan_LBD domain-containing protein.
   
 0.868
CHRNB1
Cholinergic receptor nicotinic beta 1 subunit.
    
 
 0.774
CHRNA5
Cholinergic receptor nicotinic alpha 5 subunit.
   
 0.729
RAPSN
Receptor associated protein of the synapse.
   
 
 0.722
MED19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.708
EIF4E2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
      
 0.708
OCRL
OCRL inositol polyphosphate-5-phosphatase.
      
 0.701
CLCN6
Chloride voltage-gated channel 6; Belongs to the chloride channel (TC 2.A.49) family.
      
 0.701
TIGD1
Tigger transposable element derived 1.
      
 0.700
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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