Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (803 aa)    
Predicted Functional Partners:
PRNP
Major prion protein; Belongs to the prion family.
    
 0.773
LGI1
Leucine rich glioma inactivated 1.
   
  
 0.735
DPP10
Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family.
   
 
 0.706
NFASC
Neurofascin.
   
  
 0.692
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
  
 0.667
KCND2
Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family.
   
 
 0.634
KCND3
Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family.
   
 
 0.634
IGLON5
IgLON family member 5.
   
  
 0.626
AMPH
Amphiphysin.
   
  
 0.622
SYP
Synaptophysin.
   
  
 0.595
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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