STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KMT2CLysine methyltransferase 2C. (4969 aa)    
Predicted Functional Partners:
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.990
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.990
WDR5
WD repeat domain 5.
   
 0.981
KDM6A
Lysine demethylase 6A.
   
 0.976
NCOA6
Nuclear receptor coactivator 6.
   
 0.971
PAXIP1
PAX interacting protein 1.
   
 0.959
PAGR1
PAXIP1 associated glutamate rich protein 1.
    
 0.954
ENSCSAP00000007692
Uncharacterized protein.
   
 0.927
LOC103221971
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.922
UTY
Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked.
   
 0.868
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.