STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMT2CLysine methyltransferase 2C. (4969 aa)    
Predicted Functional Partners:
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.994
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.993
WDR5
WD repeat domain 5.
   
 0.978
LOC103221971
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.918
NCOA6
Nuclear receptor coactivator 6.
   
 0.904
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
    
  0.879
WDR5B
WD repeat domain 5B.
   
 0.845
PRKAA1
Non-specific serine/threonine protein kinase.
   
  0.843
KDM6A
Lysine demethylase 6A.
   
 0.842
PAXIP1
PAX interacting protein 1.
   
 0.832
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.